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Stafib-1
$150 – $1,200
Products Details
Product Description
– Stafib-1 is the first selective inhibitor of the STAT5b SH2 domain, with a Ki of 44 nM and an IC50 of 154 nM[1].
Web ID
– HY-112647
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C26H24N2O11P2
References
– [1]Nagarajan Elumalai, et al. Rational development of Stafib-2: a selective, nanomolar inhibitor of the transcription factor STAT5b. Sci Rep. 2017 Apr 11;7(1):819.
CAS Number
– 1688703-26-5
Molecular Weight
– 602.42
Compound Purity
– 98.0
SMILES
– O=C(C1=CC=C2C=C(OCC(NCC3=CC=C(OP(O)(O)=O)C(OP(O)(O)=O)=C3)=O)C=CC2=C1)NC4=CC=CC=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– STAT
Isoform
– STAT5
Pathway
– JAK/STAT Signaling;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
