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SU11652
SKU
HY-112452-10 mg
Category Reference compound
Tags Apoptosis;c-Kit;FGFR;PDGFR;VEGFR, Apoptosis;Protein Tyrosine Kinase/RTK, Cancer
$100 – $850
Products Details
Product Description
– SU11652 is a potent receptor tyrosine kinase (RTK) inhibitor. SU11652 also inhibits several members of the split kinase family of RTKs, including VEGFR, FGFR, PDGFR, and Kit. SU11652 can be uesd for spontaneous cancers expressing Kit mutations research[1].
Web ID
– HY-112452
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C22H27ClN4O2
References
– [1]Liao AT, et al. Inhibition of constitutively active forms of mutant kit by multitargeted indolinone tyrosine kinase inhibitors. Blood. 2002;100(2):585-593.
CAS Number
– 326914-10-7
Molecular Weight
– 414.93
Compound Purity
– 99.06
SMILES
– O=C(C1=C(C)NC(/C=C2C(NC3=C2C=C(Cl)C=C3)=O)=C1C)NCCN(CC)CC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Apoptosis;c-Kit;FGFR;PDGFR;VEGFR
Pathway
– Apoptosis;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.