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p38 MAP Kinase Inhibitor IV

$144

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Products Details

Product Description

– p38 MAP Kinase Inhibitor IV is a highly specific ATP-competitive p38α MAPK inhibitor with IC50s of 0.13 and 0.55 μM for p38α and p38β MAPK, respectively[1].

Web ID

– HY-112401

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C12H4Cl6O4S

References

– [1]Liu YC, et al. Identification of a novel competitive inhibitor of p38alpha MAPK by a human PBMC screen. Biochem Biophys Res Commun. 2007;352(3):656-661.

CAS Number

– 1638-41-1

Molecular Weight

– 456.94

SMILES

– OC1=C(Cl)C=C(Cl)C(Cl)=C1S(=O)(C2=C(O)C(Cl)=CC(Cl)=C2Cl)=O

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– p38 MAPK

Isoform

– p38α;p38β;p38δ

Pathway

– MAPK/ERK Pathway

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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