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BOS-172722
$220 – $1,400
Products Details
Product Description
– BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint with an IC50 of 11 nM and 63 nM for MPS1 (1 mM ATP) and P-MPS1, respectively. BOS-172722 also has potential for the study of various forms of breast cancer[1].
Web ID
– HY-112162
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H30N8O
References
– [1]ARYL SULFONOHYDRAZIDES. WO 2014037750 A1.
CAS Number
– 1578245-44-9
Molecular Weight
– 446.55
Compound Purity
– 98.65
SMILES
– CC1=CC2=CN=C(NC3=CC=C(C4=NN=CN4C)C=C3OCC)N=C2C(NCC(C)(C)C)=N1
Clinical Information
– Phase 1
Research Area
– Cancer
Solubility
– 1M HCl : 65 mg/mL (ultrasonic;adjust pH to 2 with HCl)|DMSO : 5 mg/mL (ultrasonic)
Target
– Mps1
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
