Download Files:
Products Details
Product Description
– GSK8175 is a non-nucleoside polymerase (NS5B) inhibitor of hepatitis C virus (HCV). GSK8175 is a sulfonamide- N-benzoxaborole analog with low in vivo clearance across preclinical species and broad-spectrum activity against HCV replicons[1].
Web ID
– HY-112047
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C27H23BClFN2O6S
References
– [1]Chong PY, et al. Design of N-Benzoxaborole Benzofuran GSK8175-Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor. J Med Chem. 2019;62(7):3254-3267.
CAS Number
– 1423007-82-2
Molecular Weight
– 568.81
SMILES
– O=C(C1=C(C(C=C2)=CC=C2F)OC3=CC(N(C4=CC(Cl)=C5C(COB5O)=C4)[S](C)(=O)=O)=C(C6CC6)C=C13)NC
Clinical Information
– Phase 1
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HCV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
