Tomivosertib
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Tomivosertib

SKU T3468-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 67 CAD through 1,968 CAD

Products Details

Product Description

– Tomivosertib (eFT508) is a potent and highly selective MNK1 and MNK2 inhibitor with an IC50 value of 1-2 nM.

Web ID

– T3468

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H20N6O2

Citations

– 1. Suarez M, Blyth G T, Mina A A, et al. Inhibitory effects of Tomivosertib in acute myeloid leukemia. Oncotarget. 2021, 12(10): 955.

References

– Kevin R Webster, et al. eFT508, a Potent and Selective Mitogen-Activated Protein Kinase Interacting Kinase (MNK) 1 and 2 Inhibitor, is Efficacious in Preclinical Models of Diffuse Large B-Cell Lymphoma (DLBCL). Abstract#1554.

CAS Number

– 1849590-01-7

Molecular Weight

– C17H20N6O2

Compound Purity

– 0.9734

SMILES

– Cc1cc(Nc2cc(N)ncn2)c(=O)n2c1C(=O)NC21CCCCC1

Pathway

– Apoptosis|||Cell Cycle/Checkpoint|||MAPK|||Immunology/Inflammation

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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