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WU-04
Products Details
Product Description
– WU-04 is a non-covalent inhibitor of SARS-CoV-2, targeting the 3CLpro protein. WU-04 has high inhibitory effect on the 3CLpro protein of 6 SARS-CoV-2 variants (Alpha, Beta, Gamma, Delta, Lambda and Omicron) and 2 coronaviruses (SARS-CoV and MERS-CoV)[1].
Web ID
– HY-149535
Shipping
– Room temperature
Molecular Formula
– C24H24BrN5O4
References
– [1]Wu J, et al. The molecular mechanism of non-covalent inhibitor WU-04 targeting SARS-CoV-2 3CLpro and computational evaluation of its effectiveness against mainstream coronaviruses. Phys Chem Chem Phys. 2023 Sep 13;25(35):23555-23567.. .
CAS Number
– 2921711-74-0
Molecular Weight
– 526.38
SMILES
– O=C(N[C@H]1CCCC[C@H]1NC2=C([N+]([O-])=O)C=C(Br)C=C2C(NC)=O)C3=CN=CC4=CC=CC=C43
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– SARS-CoV
Pathway
– Anti-infection
Product type
– Reference compound
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