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Products Details
Product Description
– UniPR505 (Compound 14) is an EphA2 antagonist with an IC50 of 0.95 µM. UniPR505 displays anti-angiogenic properties[1].
Web ID
– HY-146375
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C39H57N3O5
References
– [1]Incerti M, et al. Optimization of EphA2 antagonists based on a lithocholic acid core led to the identification of UniPR505, a new 3α-carbamoyloxy derivative with antiangiogenetic properties. Eur J Med Chem. 2020 Mar 1;189:112083.
CAS Number
– 2938227-14-4
Molecular Weight
– 647.89
SMILES
– [H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@@H]([C@]4(CC[C@]3([H])[C@]1(CC[C@H](C2)OC(NCC)=O)C)C)[C@@H](CCC(N[C@@H](CC5=CNC6=C5C=CC=C6)CC(O)=O)=O)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ephrin Receptor
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
