TT-012
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TT-012

SKU T77743-1 mg Category Brand:

Price range: 61 CAD through 2,544 CAD

Products Details

Product Description

– TT-012 has anti-tumor activity, selectively binds dynamic MITF and disrupts the dimer formation and DNA binding of the latter. TT-012 can inhibit the transcription of MITF in B16F10 melanoma cells. TT-012 inhibited the growth and metastasis of MITF melanoma cells in animal models. TT-012 is less cytotoxic to liver and immune cells.

Web ID

– T77743

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H15N3O4

References

– Liu Z, et al. A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy. Cell Res. 2023 Jan;33(1):55-70.

CAS Number

– 1164471-33-3

Molecular Weight

– C19H15N3O4

Compound Purity

– 0.9991

SMILES

– N(C(/C=C/C1=CC=CO1)=O)C=2N=C(NC(/C=C/C3=CC=CO3)=O)C=CC2

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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