Tripamide

$178$570

Products Details

Product Description

– Tripamide is an orally active sulfonamide-derived diuretic antihypertensive agent[1].

Web ID

– HY-106570

Shipping

– Room temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C16H20ClN3O3S

References

– [1]H Asada, et al. Effects of N-(4-azo-endo-tricyclo[5.2.1.0.(2.6)]-decan-4-yl)-4-chloro-3-sulfamoylbenzamide (E614; tripamide) on vascular smooth muscles. Gen Pharmaco. 1982;13(3):215-23.|[2]Philip Hampel, et al. Azosemide is more potent than bumetanide and various other loop diuretics to inhibit the sodium-potassium-chloride-cotransporter human variants hNKCC1A and hNKCC1B. Sci Rep. 2018 Jun 29;8(1):9877.

CAS Number

– 73803-48-2

Molecular Weight

– 369.87

SMILES

– O=C(C(C=C1)=CC([S](N)(=O)=O)=C1Cl)NN2C[C@@]3([H])[C@](C2)([H])[C@@H]4C[C@H]3CC4

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– Potassium Channel

Pathway

– Membrane Transporter/Ion Channel

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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