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Tripamide
SKU
HY-106570-10 mg
Category Reference compound
Tags Membrane Transporter/Ion Channel, Metabolic Disease, Potassium Channel
$178 – $570
Products Details
Product Description
– Tripamide is an orally active sulfonamide-derived diuretic antihypertensive agent[1].
Web ID
– HY-106570
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C16H20ClN3O3S
References
– [1]H Asada, et al. Effects of N-(4-azo-endo-tricyclo[5.2.1.0.(2.6)]-decan-4-yl)-4-chloro-3-sulfamoylbenzamide (E614; tripamide) on vascular smooth muscles. Gen Pharmaco. 1982;13(3):215-23.|[2]Philip Hampel, et al. Azosemide is more potent than bumetanide and various other loop diuretics to inhibit the sodium-potassium-chloride-cotransporter human variants hNKCC1A and hNKCC1B. Sci Rep. 2018 Jun 29;8(1):9877.
CAS Number
– 73803-48-2
Molecular Weight
– 369.87
SMILES
– O=C(C(C=C1)=CC([S](N)(=O)=O)=C1Cl)NN2C[C@@]3([H])[C@](C2)([H])[C@@H]4C[C@H]3CC4
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Potassium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.