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Tivanisiran
SKU
HY-132596-10 mg
Category Oligonucleotides
Tags Epigenetics;Membrane Transporter/Ion Channel;Neuronal Signaling, Neurological Disease, Small Interfering RNA (siRNA);TRP Channel
$720 – $2,450
Products Details
Product Description
– Tivanisiran (SYL1001) is a siRNA used for the study of dry eye disease. Tivanisiran was designed to silence transient receptor potential vanilloid 1 (TRPV1) mRNA[1].
Web ID
– HY-132596
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– N/A
References
– [1]Anne-Marie Bleau, et al. Development of tivanisiran, a topical siRNA designed to|[2]Javier Moreno-Montañés, et al. Tivanisiran, a novel siRNA for the treatment of dry eye disease. Expert Opin Investig Drugs. 2018 Apr;27(4):421-426.
CAS Number
– 1848224-71-4
Molecular Weight
– 12068.30 (AS: 5294.6 + SS: 6125.7)
Compound Purity
– 92.62
SMILES
– [Tivanisiran]
Clinical Information
– Phase 3
Research Area
– Neurological Disease
Solubility
– H2O : 100 mg/mL (ultrasonic)
Target
– Small Interfering RNA (siRNA);TRP Channel
Pathway
– Epigenetics;Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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