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TH470
$210 – $1,250
Products Details
Product Description
– TH470 is a highly selective LIMK1/2 (LIM kinase1/2) inhibitor (LIMK1 IC50=9.8 nM; LIMK2 IC50=13 nM), and can be used in orphan disease research[1].
Web ID
– HY-151539
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C30H31N5O5S2
References
– [1]Hanke T, et al. Development and Characterization of Type I, Type II, and Type III LIM-Kinase Chemical Probes. J Med Chem. 2022 Oct 13;65(19):13264-13287.
CAS Number
– 2834739-51-2
Molecular Weight
– 605.73
Compound Purity
– 99.57
SMILES
– CC(C(NC1=NC=C(S1)C(NCCN(C(C2=CC=C(C=C2)S(=O)(NC3=CC=CC=C3)=O)=O)CC4=CC=CC=C4)=O)=O)C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– LIM Kinase (LIMK)
Isoform
– LIMK1;LIMK2
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
