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Products Details
Product Description
– STING agonist-9 (Compound 45) is a potent STING agonist with an EC50 of 1.2 nM and 32.82 μM against h-STING and m-STING, respectively. STING agonist-9 shows antitumor activity[1].
Web ID
– HY-147834
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C39H47N13O6S
References
– [1]Niu J, et al. Discovery of novel Thieno[2,3-d]imidazole derivatives as agonists of human STING for antitumor immunotherapy using systemic administration. Eur J Med Chem. 2022 Aug 5;238:114482.
CAS Number
– 2653337-73-4
Molecular Weight
– 825.94
SMILES
– O=C(C1=CC(OCCCN2CCOCC2)=C3C(N=C(NC(C4=CC(C)=NN4CC)=O)N3C/C=C/CN5C(NC(C6=CC(C)=NN6CC)=O)=NC7=C5SC(C(N)=O)=C7)=C1)N
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– STING
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
