Sofnobrutinib
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Sofnobrutinib

SKU T72865-25 mg Category Brand:

Price range: 3,152 CAD through 5,440 CAD

Products Details

Product Description

– Sofnobrutinib (AS-0871) is an orally active, selective inhibitor of Bruton’s tyrosine kinase (BTK) with IC50 values of 4.2 nM for activated BTK and 0.39 nM for unactivated BTK. It has an IC50 of 24 μM against hERG, exhibits strong metabolic stability and bioavailability, induces a weak passive cutaneous anaphylaxis reaction, and demonstrates anti-inflammatory properties in a mouse model of collagen-induced arthritis.

Web ID

– T72865

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H23FN8O2

CAS Number

– 1646608-10-7

Molecular Weight

– C26H23FN8O2

SMILES

– C(O)C1=C(C=CC=C1C=2N=C(NC3=CN(C)N=C3)N=C(N)N2)N4C(=O)C=5C(C=C4)=CC(=CC5F)C6CC6

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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