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SL651498
SKU
HY-114871-Get quote
Category Reference compound
Tags GABA Receptor, Membrane Transporter/Ion Channel;Neuronal Signaling, Neurological Disease
Products Details
Product Description
– SL651498 is a full agonist of α2 and α3 GABAA receptors, and a partial agonist of α1 and α5 GABAA receptors. SL651498 shows anxiolytic and anticonvulsant activities[1].
Web ID
– HY-114871
Shipping
– Room temperature
Molecular Formula
– C23H20FN3O2
References
– [1]G Griebel, et al. SL651498: an anxioselective compound with functional selectivity for alpha2- and alpha3-containing gamma-aminobutyric acid(A) (GABA(A)) receptors. J Pharmacol Exp Ther. 2001 Aug;298(2):753-68.
CAS Number
– 205881-86-3
Molecular Weight
– 389.42
SMILES
– O=C(C1=CN(C(C2=C1C3=C(C=CC(F)=C3)N2C)=O)C4=CC=CC=C4)N5CCCC5
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– GABA Receptor
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.