Products Details

Product Description

– SL651498 is a full agonist of α2 and α3 GABAA receptors, and a partial agonist of α1 and α5 GABAA receptors. SL651498 shows anxiolytic and anticonvulsant activities[1].

Web ID

– HY-114871

Shipping

– Room temperature

Molecular Formula

– C23H20FN3O2

References

– [1]G Griebel, et al. SL651498: an anxioselective compound with functional selectivity for alpha2- and alpha3-containing gamma-aminobutyric acid(A) (GABA(A)) receptors. J Pharmacol Exp Ther. 2001 Aug;298(2):753-68.

CAS Number

– 205881-86-3

Molecular Weight

– 389.42

SMILES

– O=C(C1=CN(C(C2=C1C3=C(C=CC(F)=C3)N2C)=O)C4=CC=CC=C4)N5CCCC5

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– GABA Receptor

Pathway

– Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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