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Product Description
– SARS-CoV-2-IN-65 (compound 2f (81)) is a potent,orally active and reversible SARS-CoV-2 entry inhibitor. SARS-CoV-2-IN-65 inhibits the pseudovirus entry in a ACE2-dependent pathway, via mainly inhibiting RBD:ACE2 interaction and TMPRSS2 activity in Calu-3 cells[1].
Web ID
– HY-156441
Shipping
– Room temperature
Molecular Formula
– C22H18N2O4
References
– [1]Srinivasa Rao Palla, et al. Synthesis, evaluation, and mechanism of 1-(4-(arylethylenylcarbonyl)phenyl)-4-carboxy-2-pyrrolidinones as potent reversible SARS-CoV-2 entry inhibitors. Antiviral Res. 2023 Oct 18:219:105735.
Molecular Weight
– 374.39
SMILES
– O=C1N(C2=CC=C(C(/C=C/C3=C4C(NC=C4)=CC=C3)=O)C=C2)CC(C(O)=O)C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– SARS-CoV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
