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Products Details
Product Description
– S100A2-p53-IN-1 (compound 51) is a S100A2-p53 interactions inhibitor. S100A2 is a Ca2+ binding protein with implications in cell signaling and is known to be upregulated in pancreatic cancer. S100A2-p53-IN-1 can inhibit the growth of the MiaPaCa-2 pancreatic cancer cell line (GI50 of 1.2-3.4 μM)[1].
Web ID
– HY-145900
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H20F6N2O4S
References
– [1]Sun J, et, al. 3,5-Bis(trifluoromethyl)phenylsulfonamides, a novel pancreatic cancer active lead. Investigation of the terminal aromatic moiety. Bioorg Med Chem Lett. 2022 Apr 1;61:128591.
CAS Number
– 2766609-08-7
Molecular Weight
– 498.44
SMILES
– O=S(NCCCNCC1COC2=C(O1)C=CC=C2)(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– MDM-2/p53
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
