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Rutin
$45 – $82
Products Details
Product Description
– Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin can cross the blood brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress[1][2][3].
Web ID
– HY-N0148
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C27H30O16
Citations
– Antioxidants (Basel). 2023 Nov 7, 12(11), 1974.|Food Chem. 16 December 2021, 131872.|Food Chem. 2022: 134807.|iScience. 2023 Sep 6.|Pharmacogn Mag. 2023 Oct 12.|Phytomedicine. 2023 Feb 4;112:154700.|Adv Sci (Weinh). 2022 Oct 18;e2203088.
References
– [1]Ghorbani A. Mechanisms of antidiabetic effects of flavonoid rutin. Biomed Pharmacother. 2017;96:305-312.|[2]Habtemariam S. Rutin as a Natural Therapy for Alzheimer’s Disease: Insights into its Mechanisms of Action. Curr Med Chem. 2016;23(9):860-873.|[3]Xu PX, et al. Rutin improves spatial memory in Alzheimer’s disease transgenic mice by reducing Aβ oligomer level and attenuating oxidative stress and neuroinflammation. Behav Brain Res. 2014;264:173-180.|[4]Abdel-Aleem GA, et al. Rutin hydrate ameliorates cadmium chloride-induced spatial memory loss and neural apoptosis in rats by enhancing levels of acetylcholine, inhibiting JNK and ERK1/2 activation and activating mTOR signalling. Arch Physiol Biochem. 2018;124(4):367-377.
CAS Number
– 153-18-4
Molecular Weight
– 610.52
Compound Purity
– 98.06
SMILES
– O=C1C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO[C@H]3[C@@H]([C@@H]([C@H]([C@H](C)O3)O)O)O)O2)O)O)O)=C(C4=CC=C(O)C(O)=C4)OC5=CC(O)=CC(O)=C15
Clinical Information
– Launched
Research Area
– Inflammation/Immunology; Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– Amyloid-β;Apoptosis;Autophagy;Endogenous Metabolite
Pathway
– Apoptosis;Autophagy;Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
