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RS 39604
$490 – $790
Products Details
Product Description
– RS 39604 is a potent, selective, and orally active 5-HT4 receptor antagonist with a pKi of 9.1 in guinea pig striatal membranes. RS 39604 displays a low affinity (pKi<6.5) for 5-HT1A, 5-HT2C, 5-HT3, α1c, D1, D2, M1, M2, AT1, B1 and opioid mu receptors and moderate affinity for δ1, (pKi=6.8) and δ2 (pKi=7.8) sites[1].
Web ID
– HY-101343
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C26H37Cl2N3O6S
References
– [1]Hegde SS, et al. RS 39604: a potent, selective and orally active 5-HT4 receptor antagonist. Br J Pharmacol. 1995;115(6):1087-1095.
CAS Number
– 167710-87-4
Molecular Weight
– 590.56
Compound Purity
– 98.0
SMILES
– CS(=O)(NCCN1CCC(CCC(C2=CC(Cl)=C(N)C=C2OCC3=CC(OC)=CC(OC)=C3)=O)CC1)=O.Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– 5-HT Receptor
Isoform
– 5-HT4 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
