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Ridogrel
SKU
HY-A0221-10mM/1mL
Category Reference compound
Tags GPCR/G Protein, Inflammation/Immunology, Prostaglandin Receptor
$90 – $99
Products Details
Product Description
– Ridogrel (R 68070) is an orally active combined thromboxane A2 synthetase inhibitor and thromboxane A2/prostaglandin endoperoxide receptor blocker. Ridogrel is potent antiplatelet agent. Anti-inflammatory activities[1][2][3].
Web ID
– HY-A0221
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C18H17F3N2O3
References
– [1]De Clerck F, et al. R 68 070: thromboxane A2 synthetase inhibition and thromboxane A2/prostaglandin endoperoxide receptor blockade combined in one molecule–II. Pharmacological effects in vivo and ex vivo. Thromb Haemost. 1989;61(1):43-49.|[2]Di Perri T, et al. Ridogrel, una nuova molecula antiaggregante piastrinica a doppio meccanismo d’azione. Profilo farmacologico e clinico [Ridogrel, a new platelet antiaggregant molecule with a double mechanism of action. A pharmacological and clinical profile]. Recenti Prog Med. 1991;82(10):533-540.|[3]Carty E, et al. Ridogrel, a dual thromboxane synthase inhibitor and receptor antagonist: anti-inflammatory profile in inflammatory bowel disease. Aliment Pharmacol Ther. 2000;14(6):807-817.
CAS Number
– 110140-89-1
Molecular Weight
– 366.33
Compound Purity
– 99.64
SMILES
– O=C(O)CCCCO/N=C(C1=CC=CN=C1)C2=CC=CC(C(F)(F)F)=C2
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Prostaglandin Receptor
Isoform
– EP
Pathway
– GPCR/G Protein
Product type
– Reference compound
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