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PIP-199
$234 – $585
Products Details
Product Description
– PIP-199 is a selective inhibitor of RMI (RecQ-mediated genome instability protein) core complex/MM2 interaction, with an IC50 of 36 μM. PIP-199 can be used for the research of sensitizing resistant tumors to DNA crosslinking chemotherapeutics[1].
Web ID
– HY-124325
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C27H28N4O3
References
– [1]Andrew F. Voter, et al. A high throughput screening strategy to identify protein-protein interaction inhibitors that block the Fanconi anemia DNA repair pathway. J Biomol Screen. 2016 Jul; 21(6): 626–633.
CAS Number
– 622795-76-0
Molecular Weight
– 456.54
Compound Purity
– 98.0
SMILES
– O=C(N1CCN(C(C2=C(C3=CC=CC=C3)N(O)C4=C2C=CC=C4)C5=NC=CC=C5)CC1)OCC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 41.67 mg/mL (ultrasonic;warming;heat to 80°C)
Target
– DNA Alkylator/Crosslinker
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
