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PF-4479745
$314
Only 1000 item(s) left in stock.
Products Details
Product Description
– PF-4479745 is a potent and selective 5-HT2C receptor agonist (EC50: 10 nM, ki: 15 nM). PF-4479745 can be used in the research of cardiovascular disease like hypertension[1].
Web ID
– HY-118339
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C17H22N4
References
– [1]R Ian Storer, et al. Multiparameter optimization in CNS drug discovery: design of pyrimido[4,5-d]azepines as potent 5-hydroxytryptamine 2C (5-HTâ‚‚C) receptor agonists with exquisite functional selectivity over 5-HTâ‚‚A and 5-HTâ‚‚B receptors. J Med Chem. 2014 Jun 26;57(12):5258-69.
CAS Number
– 1065110-43-1
Molecular Weight
– 282.38
SMILES
– CNC1=C2C([C@H](CNCC2)C)=NC(CC3=CC=CC=C3)=N1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– 5-HT Receptor
Isoform
– 5-HT1 Receptor;5-HT2 Receptor;5-HT6 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
