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Pelubiprofen
SKU
HY-12383-10 mg
Category Reference compound
Tags COX, Immunology/Inflammation, Inflammation/Immunology; Neurological Disease
$60 – $460
Products Details
Product Description
– Pelubiprofen, an orally active and non-steroidal anti-inflammatory drug, is a member of the 2-arylpropionic acid family and has relatively selective effects on COX-2 activity. Pelubiprofen inhibits COX activity and the transforming growth factor-β activated kinase 1-IκB kinase β-NF-κB pathway, and has significant anti-inflammatory and analgesic effects[1].
Web ID
– HY-12383
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C16H18O3
References
– [1]Choi IA, Baek HJ, et al. Comparison of the efficacy and safety profiles of a pelubiprofen versus celecoxib in patients with rheumatoid arthritis: a 6-week, multicenter, randomized, double-blind, phase III, non-inferiority clinical trial. BMC Musculoskelet Disord. 2014 Nov 18;15:375.
CAS Number
– 69956-77-0
Molecular Weight
– 258.31
SMILES
– O=C(O)C(C)C1=CC=C(/C=C2C(CCCC/2)=O)C=C1
Clinical Information
– Launched
Research Area
– Inflammation/Immunology; Neurological Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– COX
Isoform
– COX-2
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.