Pelubiprofen

$60$460

Products Details

Product Description

– Pelubiprofen, an orally active and non-steroidal anti-inflammatory drug, is a member of the 2-arylpropionic acid family and has relatively selective effects on COX-2 activity. Pelubiprofen inhibits COX activity and the transforming growth factor-β activated kinase 1-IκB kinase β-NF-κB pathway, and has significant anti-inflammatory and analgesic effects[1].

Web ID

– HY-12383

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C16H18O3

References

– [1]Choi IA, Baek HJ, et al. Comparison of the efficacy and safety profiles of a pelubiprofen versus celecoxib in patients with rheumatoid arthritis: a 6-week, multicenter, randomized, double-blind, phase III, non-inferiority clinical trial. BMC Musculoskelet Disord. 2014 Nov 18;15:375.

CAS Number

– 69956-77-0

Molecular Weight

– 258.31

SMILES

– O=C(O)C(C)C1=CC=C(/C=C2C(CCCC/2)=O)C=C1

Clinical Information

– Launched

Research Area

– Inflammation/Immunology; Neurological Disease

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– COX

Isoform

– COX-2

Pathway

– Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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