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Products Details
Product Description
– P-CAB agent 1 (compound B19) is a highly potent potassium-competitive acid blocker agent with an IC50 value of 60.50 nM for H+/K+-ATPase. P-CAB agent 1 has acceptable oral absorption in rats. P-CAB agent 1 can be used for researching acid-related disorders (ARDs)[1].
Web ID
– HY-150555
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C26H23FN4O
References
– [1]Wang X, et al. Design, synthesis and biological evaluation of novel 5-methyl-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole derivatives as potent potassium-competitive acid blockers. Bioorg Med Chem. 2022 Jun 15;64:116765.
CAS Number
– 2374139-68-9
Molecular Weight
– 426.49
SMILES
– O=C(N)C1=CC(C2=CC=CC(CN3N=C4CN(CC4=C3C5=CC=CC=C5F)C)=C2)=CC=C1
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Potassium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
