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ONO-8590580
$76 – $1,250
Products Details
Product Description
– ONO-8590580 is a GABAA α5 negative allosteric modulator.
Web ID
– HY-112788
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C21H21FN6
References
– [1]Kawaharada S, et al. ONO-8590580, a Novel GABAAα5 Negative Allosteric Modulator Enhances Long-Term Potentiation and Improves Cognitive Deficits in Preclinical Models. J Pharmacol Exp Ther. 2018 Jul;366(1):58-65.
CAS Number
– 1802661-73-9
Molecular Weight
– 376.43
Compound Purity
– 99.13
SMILES
– CN1C=C(C2=CN=C(NC3=C(F)C(C)=C4N=CN(CC5CC5)C4=C3)C=C2)N=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 62.5 mg/mL (ultrasonic)
Target
– GABA Receptor
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
