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NNC05-2090 (hydrochloride)
$130 – $1,480
Products Details
Product Description
– NNC05-2090 (hydrochloride) is a GABA uptake inhibitor. NNC05-2090 is a betaine/GABA transporter (BGT-1) inhibitor with an IC50 value of 10.6 μM. NNC05-2090 can be used for the research of epilepsy and neurological disease[1][2].
Web ID
– HY-103509
Shipping
– Room temperature
Molecular Formula
– C27H31ClN2O2
References
– [1]Dalby NO, et al. Anticonvulsant properties of two GABA uptake inhibitors NNC 05-2045 and NNC 05-2090, not acting preferentially on GAT-1. Epilepsy Res. 1997 Jul;28(1):51-61.|[2]Jinzenji A, et al. Antiallodynic action of 1-(3-(9H-Carbazol-9-yl)-1-propyl)-4-(2-methyoxyphenyl)-4-piperidinol (NNC05-2090), a betaine/GABA transporter inhibitor. J Pharmacol Sci. 2014;125(2):217-26.
CAS Number
– 184845-18-9
Molecular Weight
– 451.00
SMILES
– OC1(CCN(CC1)CCCN2C3=C(C4=C2C=CC=C4)C=CC=C3)C5=C(OC)C=CC=C5.Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– GABA Receptor
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
