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Neochlorogenic acid
SKU
HY-N0722-1 mg
Category Natural Products
Tags Apoptosis;Immunology/Inflammation;NF-κB, COX;Interleukin Related;NF-κB;TNF Receptor, Inflammation/Immunology; Cancer
$71 – $240
Products Details
Product Description
– Neochlorogenic acid is a natural polyphenolic compound found in dried fruits and other plants. Neochlorogenic acid inhibits the production of TNF-α and IL-1β. Neochlorogenic acid suppresses iNOS and COX-2 protein expression. Neochlorogenic acid also inhibits phosphorylated NF-κB p65 and p38 MAPK activation.
Web ID
– HY-N0722
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C16H18O9
References
– [1]Kim M, et al. Neochlorogenic Acid Inhibits Lipopolysaccharide-Induced Activation and Pro-inflammatory Responses in BV2 Microglial Cells. Neurochem Res. 2015 Sep;40(9):1792-8.
CAS Number
– 906-33-2
Molecular Weight
– 354.31
Compound Purity
– 99.07
SMILES
– O=C([C@]1(O)C[C@@H](OC(/C=C/C2=CC=C(O)C(O)=C2)=O)[C@@H](O)[C@H](O)C1)O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)|H2O : 2 mg/mL (ultrasonic)
Target
– COX;Interleukin Related;NF-κB;TNF Receptor
Isoform
– CD40;COX-2;IL-1;RelA/p65
Pathway
– Apoptosis;Immunology/Inflammation;NF-κB
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.