Products Details

Product Description

– LY 293284 is a potent and selective 5-HT1A receptor agonist. LY 293284 results in a significant drop in core temperature and consumes more food in cholestasis rat induced by bile duct resection[1][2].

Web ID

– HY-120396

Shipping

– Room temperature

Molecular Formula

– C19H26N2O

References

– [1]Marona-Lewicka D, et al. Aripiprazole (OPC-14597) fully substitutes for the 5-HT1A receptor agonist LY293284 in the drug discrimination assay in rats. Psychopharmacology (Berl). 2004;172(4):415-421.|[2]Burak KW, et al. Increased midbrain 5-HT1A receptor number and responsiveness in cholestatic rats. Brain Res. 2001;892(2):376-379.

CAS Number

– 141318-62-9

Molecular Weight

– 298.42

SMILES

– CC(C1=C2C3=C(C=C1)NC=C3C[C@@H](C2)N(CCC)CCC)=O

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– 5-HT Receptor

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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