LP44 (hydrochloride)

$90$820

Products Details

Product Description

– LP44 (hydrochloride) is a selective 5-HT7 agonist with Ki of 0.22 nM. LP44 (hydrochloride) induces hypothermic effect in a dose-dependent manner by intracerebroventricular injection. LP44 (hydrochloride) not causes considerable hypothermic response by intraperitoneal administration[1].

Web ID

– HY-103101

Storage Temperature

– -20°C (Powder, sealed storage, away from moisture)

Shipping

– Blue Ice

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C27H38ClN3OS

References

– [1]Naumenko VS,et al. On the role of brain 5-HT7 receptor in the mechanism of hypothermia: comparison with hypothermia mediated via 5-HT1A and 5-HT3 receptor. Neuropharmacology. 2011 Dec;61(8):1360-5.

CAS Number

– 824958-12-5

Molecular Weight

– 488.13

Compound Purity

– 98.06

SMILES

– O=C(CCCCCN1CCN(C(C=CC=C2)=C2SC)CC1)NC3C4=CC=CC=C4CCC3.Cl

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– 5-HT Receptor

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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