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Larixyl acetate
$70 – $340
Products Details
Product Description
– Larixyl acetate is a potent and selective TRPC6 inhibitor with IC50 values of 0.58 μM and 6.83 μM against hTRPC6-YFP and hTRPC3-YFP, respectively. Larixyl acetate prevents HPV and is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction[1][2].
Web ID
– HY-101795
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H36O3
References
– [1]Urban N, et al. Identification and Validation of Larixyl Acetate as a Potent TRPC6 Inhibitor. Mol Pharmacol. 2016 Jan;89(1):197-213. |[2]Chen X, et al. The TRPC6 inhibitor, larixyl acetate, is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction. J Neuroinflammation. 2019 Jan 31;16(1):21.
CAS Number
– 4608-49-5
Molecular Weight
– 348.52
Compound Purity
– 99.46
SMILES
– CC(CCC1)(C)[C@]([C@@]1(C)[C@H]2CC[C@](C)(O)C=C)([H])[C@@H](OC(C)=O)CC2=C
Clinical Information
– No Development Reported
Research Area
– Infection; Neurological Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– HPV;TRP Channel
Isoform
– TRPC
Pathway
– Anti-infection;Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
