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Products Details
Product Description
– ITH12711 is a PP2A ligand. ITH12711 is able to cross the blood-brain barrier (BBB). ITH12711 exerts neuroprotection via restoration of PP2A-phosphatase activity[1].
Web ID
– HY-149097
Shipping
– Room temperature
Molecular Formula
– C12H20O5
References
– [1]Raquel L Arribas, et al. C-glycosides analogues of the okadaic acid central fragment exert neuroprotection via restoration of PP2A-phosphatase activity: A rational design of potential drugs for Alzheimer’s disease targeting tauopathies. Eur J Med Chem. 2023 May 5;251:115245.
Molecular Weight
– 244.28
SMILES
– CC1(OC[C@H]2O[C@@H](C=C[C@@H]2O1)C[C@@H](CO)O)C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Phosphatase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
