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Products Details
Product Description
– Isopropyl unoprostone (Unoprostone isopropyl ester), an analogue of a prostaglandin metabolite, is a potent large conductance Ca2+-activated K+ (BK) channels activator. Isopropyl unoprostone has antiglaucoma effects, lowering intraocular pressure (IOP) by increasing aqueous humour outflow. Isopropyl unoprostone can improve retinal sensitivity and the protection of central retinal sensitivity[1][2].
Web ID
– HY-109545
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C25H44O5
References
– [1]Haria M, et al. Unoprostone (isopropyl unoprostone). Drugs Aging. 1996 Sep;9(3):213-8; discussion 219-20. |[2]Tsuruma K, et al. Unoprostone reduces oxidative stress- and light-induced retinal cell death, and phagocytotic dysfunction, by activating BK channels. Mol Vis. 2011;17:3556-65.
CAS Number
– 120373-24-2
Molecular Weight
– 424.61
SMILES
– O=C(OC(C)C)CCC/C=CC[C@@H]1[C@@H](CCC(CCCCCCC)=O)[C@H](O)C[C@@H]1O
Clinical Information
– Launched
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Potassium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
