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I-SAP
$170
Only 1000 item(s) left in stock.
Products Details
Product Description
– I-SAP is a radioiodinated TXA2/PGH2 receptor antagonist. The bind between I-SAP and the receptors, is inhibited by the histidine modifying reagent diethyl-pyrocarbonate (DEPC)[1][2].
Web ID
– HY-118044
Shipping
– Room temperature
Molecular Formula
– C22H30INO4S
References
Р[1]Saussy DL Jr, et al. Binding of a novel radioiodinated thromboxane A2/prostaglandin H2 antagonist to guinea pig lung membranes. Eicosanoids. 1992;5(1):1-4. |[2]Schr̦r K, et al. Inhibition of ligand binding to thromboxane A2/prostaglandin H2 receptors by diethylpyrocarbonate. Protection by receptor ligands and reversal by hydroxylamine. Biochem Pharmacol. 1995 Mar 30;49(7):921-7.
CAS Number
– 133538-58-6
Molecular Weight
– 531.45
SMILES
– OC(CCC/C=CC[C@H]1[C@@](C[C@]2([H])C[C@@H]1N[S](=O)(C(C=C3)=CC=C3I)=O)([H])C2(C)C)=O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Prostaglandin Receptor
Isoform
– TXA2/TP
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
