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Products Details
Product Description
– HIV-1 inhibitor-59 (Compound I-5b) is a HIV-1 inhibitor, with EC50s of 5.62-171 nM against the wild-type (WT) and mutant HIV-1 strains. HIV-1 inhibitor-59 has moderate RT enzyme inhibitory activity (IC50: 0.094-12.0 μM)[1].
Web ID
– HY-155114
Shipping
– Room temperature
Molecular Formula
– C28H28FN5O3S
References
– [1]Song H, et al. 5-Cyano substituted diarylpyridines as potent HIV-1 NNRTIs: Rational design, synthesis, and activity evaluation. Eur J Med Chem. 2023 Nov 5;259:115686.
Molecular Weight
– 533.62
SMILES
– N#CC1=CC(C)=C(OC2=C(F)C=C(C#N)C(NC3CCN(CC4=CC=C(S(C)(=O)=O)C=C4)CC3)=N2)C(C)=C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HIV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
