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Products Details
Product Description
– HIV-1 inhibitor-57 (Compound 12g) is a HIV inhibitor. HIV-1 inhibitor-57 is active against wild-type and five prevalent NNRTI-resistant HIV-1 strains with EC50 values ranging from 0.024 to 0.0010 μM. HIV-1 inhibitor-57 forms additional interactions with residues around the binding site in HIV-1 RT[1].
Web ID
– HY-149350
Shipping
– Room temperature
Molecular Formula
– C25H24FN5O3S
References
– [1]Jiang X, et al. Discovery of novel diarypyrimidine derivatives bearing six-membered non-aromatic heterocycles as potent HIV-1 NNRTIs with improved anti-resistance and drug-like profiles. Eur J Med Chem. 2023 Oct 5;258:115605.
CAS Number
– 2745197-24-2
Molecular Weight
– 493.55
SMILES
– CC1=C(OC2=CC=NC(NC3=CC(F)=C(N4CCS(CC4)(=O)=O)C=C3)=N2)C(C)=CC(/C=C/C#N)=C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HIV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
