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Products Details
Product Description
– HIV-1 inhibitor-42 (compound 5b) is a potent HIV-1 inhibitor, with an IC50 of 0.06 μM. HIV-1 inhibitor-42 inhibits HIV-1 RT RNA-dependent DNA polymerase and DNA-dependent DNA polymerase, with IC50 values of 0.518 and 0.072 μM[1].
Web ID
– HY-147903
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C22H20N2O5S
References
– [1]Yi-MingLi, et al. Design, synthesis and anti-HIV evaluation of 5-alkyl- 6-(benzo[d][1,3]dioxol-5-alkyl)-2-mercaptopyrimidin-4(3H)-ones as potent HIV-1 NNRTIs. September 2020;102:104041.
CAS Number
– 2459929-46-3
Molecular Weight
– 424.47
SMILES
– O=C1NC(SCC(C2=CC=C(O)C=C2)=O)=NC(CC3=CC=C(OCO4)C4=C3)=C1CC
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HIV
Isoform
– HIV-1
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
