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Products Details
Product Description
– HDAC-IN-66 (compound 2F) is a selective HDAC inhibitor and Pomalidomide (HY-10984) derivative that potently inhibits hematological tumor cells[1].
Web ID
– HY-157215
Shipping
– Room temperature
Molecular Formula
– C27H23N5O5
References
– [1]Chen D et al. Serendipitous discovery of Class I HDAC inhibitors from rational design of molecular glue degraders targeting HDAC. Eur J Med Chem. 2023 Nov 19;263:115926.
Molecular Weight
– 497.50
SMILES
– NC1=CC=CC=C1NC(C2=CC=C(CNC3=CC=CC(C(N4C5C(NC(CC5)=O)=O)=O)=C3C4=O)C=C2)=O
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– HDAC
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
