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hACC2-IN-1
SKU
HY-147376-Get quote
Category Reference compound
Tags Acetyl-CoA Carboxylase, Metabolic Disease, Metabolic Enzyme/Protease
Products Details
Product Description
– hACC2-IN-1 is a potent acetyl-CoA carboxylase 2 (ACC2) inhibitor, with an IC50 value of 2.5 μM (hACC2). hACC2-IN-1 could be used for obesity research[1].
Web ID
– HY-147376
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C23H32N2O4S
References
– [1]Bengtsson C, et al. Design of small molecule inhibitors of acetyl-CoA carboxylase 1 and 2 showing reduction of hepatic malonyl-CoA levels in vivo in obese Zucker rats. Bioorg Med Chem. 2011 May 15;19(10):3039-53.
CAS Number
– 192323-14-1
Molecular Weight
– 432.58
SMILES
– CC(C)(OC(NC[C@H]1CC[C@@H](CC1)CNS(=O)(C2=CC3=C(C=CC=C3)C=C2)=O)=O)C
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Acetyl-CoA Carboxylase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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