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Products Details
Product Description
– GSK852 is a highly potent, second bromodomain (BD2)-selective, bromo and extra-terminal domain (BET) inhibitor (pIC50 = 7.9).
Web ID
– HY-115867
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H26N2O4
References
– [1]Lucas SCC, et al. Optimization of a Series of 2,3-Dihydrobenzofurans as Highly Potent, Second Bromodomain (BD2)-Selective, Bromo and Extra-Terminal Domain (BET) Inhibitors. J Med Chem. 2021 Aug 12;64(15):10711-10741.
CAS Number
– 2305842-30-0
Molecular Weight
– 406.47
SMILES
– O=C(C1=CC(C(NC)=O)=C2OC[C@](C3=CC=CC=C3)(C)C2=C1)N[C@H]4[C@]5([H])C[C@@H](O)C[C@@]54[H]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
