Download Files:
FL-411
$45 – $1,000
Products Details
Product Description
– FL-411 is a potent and selective BRD4 inhibitor with an IC50 of 0.43±0.09 μM for BRD4(1).
Web ID
– HY-111102
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H19N3O2S
References
– [1]Ouyang L, et al. Discovery of a Small-Molecule Bromodomain-Containing Protein 4 (BRD4) Inhibitor That InducesAMP-Activated Protein Kinase-Modulated Autophagy-Associated Cell Death in Breast Cancer. J Med Chem. 2017 Dec 28;60(24):9990-10012.
CAS Number
– 2118944-88-8
Molecular Weight
– 341.43
Compound Purity
– 98.0
SMILES
– CN1CCC2=C(SC(N=C(C3=CC(C)=C(O)C(C)=C3)N4)=C2C4=O)C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 5.4 mg/mL (ultrasonic)
Target
– Epigenetic Reader Domain
Isoform
– BRD4
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
