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FGFR4-IN-5
$450 – $3,900
Products Details
Product Description
– FGFR4-IN-5 is a potent and selective covalent FGFR4 inhibitor with an IC50 of 6.5 nM. FGFR4-IN-5 exhibits strong anti-tumor activity in vivo and can be used for hepatocellular carcinoma research[1].
Web ID
– HY-131704
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-Kinase/protease
Molecular Formula
– C23H23Cl2N5O5
References
– [1]Haibo Liu, et al. Discovery of Selective, Covalent FGFR4 Inhibitors with Antitumor Activity in Models of Hepatocellular Carcinoma. ACS Med Chem Lett. 2020 Mar 6;11(10):1899-1904.
CAS Number
– 1628793-01-0
Molecular Weight
– 520.37
Compound Purity
– 98.06
SMILES
– CN1C2=NC(N[C@@H]3COC[C@@H]3NC(C=C)=O)=NC=C2C=C(C4=C(Cl)C(OC)=CC(OC)=C4Cl)C1=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– FGFR
Isoform
– FGFR2;FGFR4
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
