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FGFR3-IN-5
$370 – $7,500
Products Details
Product Description
– FGFR3-IN-5 is a potent and selective FGFR3 inhibitor with IC50 values of 3, 44, and 289 nM for FGFR3, FGFR2, and FGFR1, respectively. FGFR3-IN-5 can be used in research of cancer[1].
Web ID
– HY-148779
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C24H24FN7O3
References
– [1]James FB, et, al. Substituted pyrazolo[1,5-a]pyridine compounds as inhibitors of fgfr tyrosine kinases. WO2020131627.
CAS Number
– 2446664-72-6
Molecular Weight
– 477.49
Compound Purity
– 99.28
SMILES
– N#CC1=C2C(OC)=CC(C3=CN(C4CCN(CC4)C(C5(CN(C5)C(C=C)=O)F)=O)N=C3)=CN2N=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– FGFR
Isoform
– FGFR1;FGFR2;FGFR3
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.