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Products Details
Product Description
– FGFR1 inhibitor-2 is a FGFR1 inhibitor (IC50 is 4.55 μM in MDA-MB-231 cells). FGFR1 inhibitor-2 can be used for the research of metastatic triple-negative breast cancer[1].
Web ID
– HY-139376
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C25H22F5N3O3
References
– [1]Ashraf-Uz-Zaman M, et al. Design, synthesis and structure-activity relationship study of novel urea compounds as FGFR1 inhibitors to treat metastatic triple-negative breast cancer. Eur J Med Chem. 2021;209:112866.
CAS Number
– 2410612-08-5
Molecular Weight
– 507.45
SMILES
– FC(C=C1)=CC=C1C(C2=CC=C(F)C=C2)CCCCNC(NC3=CC=C([N+]([O-])=O)C(C(F)(F)F)=C3)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– FGFR
Isoform
– FGFR1
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
