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Products Details
Product Description
– FGFR1 inhibitor-10 (Compound 4i) is an FGFR1 inhibitor (IC50: 28 nM). FGFR1 inhibitor-10 inhibits the phosphorylation of FGFR1. FGFR1 inhibitor-10 has anti-angiogenic, anti-invasion activity, and anti-tumor effect[1].
Web ID
– HY-156019
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C26H30F3N7O2S
References
– [1]Li YL, et al. Design, synthesis and evaluation of novel pyrimidinylaminothiophene derivatives as FGFR1 inhibitors against human glioblastoma multiforme. Eur J Med Chem. 2023 Nov 15;260:115764.
CAS Number
– 2426769-76-6
Molecular Weight
– 561.62
SMILES
– O=C(C1=C(NC2=NC(NC3=CC=C(N4CCC(N5CCOCC5)CC4)C=C3)=NC=C2C(F)(F)F)SC=C1)NC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– FGFR
Isoform
– FGFR1
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
