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Products Details
Product Description
– FGFR-IN-7 (compound 17) is an orally active, potent and BBB-penetrated FGFR (fibroblast growth factor receptor) modulator. FGFR-IN-7 shows neuroprotective activity. FGFR-IN-7 improves brain exposure and reduced risk of phospholidosis. FGFR-IN-7 can be used for neurodegenerative diseases research[1].
Web ID
– HY-147684
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C16H21ClF2N4O2
References
– [1]Sakai H, et al. Fibroblast growth factor receptor modulators employing diamines with reduced phospholipidosis-inducing potential. Bioorg Med Chem. 2020 Jul 15;28(14):115562.
CAS Number
– 2488764-17-4
Molecular Weight
– 374.81
SMILES
– CN(C1CCN(CC1)CC2CC2(F)F)C(COC3=CC=C(N=N3)Cl)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– FGFR
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
