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Products Details
Product Description
– EphA2 agonist 1 (Compound 7bg) is a potent EphA2 receptor agonist. EphA2 agonist 1 shows great potency and selectivity toward EphA2 overexpressed glioblastoma cells and stimulates EphA2 phosphorylation[1].
Web ID
– HY-147637
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C50H58N12O12
References
– [1]Orahoske CM, et al. Dimeric small molecule agonists of EphA2 receptor inhibit glioblastoma cell growth. Bioorg Med Chem. 2020 Sep 15;28(18):115656.
CAS Number
– 2611459-57-3
Molecular Weight
– 1019.07
SMILES
– COC1=C(C=C2C(N=C(N=C2N)N3CCN(CC3)C(C4=CC(NC(OCCOCCOCCOC(NC5=CC=CC(C(N6CCN(CC6)C7=NC8=CC(OC)=C(C=C8C(N)=N7)OC)=O)=C5)=O)=O)=CC=C4)=O)=C1)OC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ephrin Receptor
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
