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Products Details
Product Description
– Envonalkib citrate is a potent and orally active inhibitor of ALK, with IC50s of 1.96 nM, 35.1 nM, and 61.3 nM for WT and mutated L1196M and G1269S-ALK. Envonalkib citrate can be used for the research of non-small cell lung cancer[1].
Web ID
– HY-145566A
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C30H34Cl2FN5O9
References
– [1]Feng G, et, al. Pyridine-substituted 2-aminopyridine protein kinase inhibitors. WO2016015676A1.
CAS Number
– 1867204-56-5
Molecular Weight
– 698.52
SMILES
– OC(CC(C(O)=O)(O)CC(O)=O)=O.COC1=CC(N2[C@H](CNCC2)C)=NC=C1C3=CN=C(N)C(O[C@@H](C4=C(C(F)=CC=C4Cl)Cl)C)=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Anaplastic lymphoma kinase (ALK)
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
