Download Files:
Enitociclib
$132 – $1,068
Products Details
Product Description
– Enitociclib ((+)-Enitociclib) is an enanthiomer of BAY-1251152 with rotation (+). Enitociclib is a potent and selective CDK9 inhibitor with an IC50 of 3 nM. Enitociclib has anti-tumour activity[1][2].
Web ID
– HY-103019
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C19H18F2N4O2S
References
– [1]Use of Arne Scholz, et al. 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-n-{4-[(s-methylsulfonimidoyl)methyl]pyridin-2-yl}pyridin-2-amine for treating diffuse large b-cell lymphoma. WO2019158517A1.|[2]Ulrich LÜCKING, et al. 5-fluoro-n-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfoximine group. WO2014076091A1.
CAS Number
– 1610358-56-9
Molecular Weight
– 404.43
Compound Purity
– 99.73
SMILES
– N=S(CC1=CC(NC2=NC=C(F)C(C3=CC=C(F)C=C3OC)=C2)=NC=C1)(C)=O.[Rotation(+)]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 113.3 mg/mL (ultrasonic;warming)
Target
– CDK
Isoform
– CDK9
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
