Products Details

Product Description

– ELX-02, also known as NB-124, is a eukaryotic ribosomal selective glycoside (ERSG) designed to increase the read-through activity in patients with nonsense mutations and enable the production of sufficient amounts of full-length functional protein to restore activity.

Web ID

– T31616

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H38N4O10

References

– Leubitz A, Frydman-Marom A, Sharpe N, van Duzer J, Campbell KCM, Vanhoutte F. Safety, Tolerability, and Pharmacokinetics of Single Ascending Doses of ELX-02, a Potential Treatment for Genetic Disorders Caused by Nonsense Mutations, in Healthy Volunteers. Clin Pharmacol Drug Dev. 2019 Jan 16. doi: 10.1002/cpdd.647. [Epub ahead of print] PubMed PMID: 30650260.

CAS Number

– 1375073-95-2

Molecular Weight

– C19H38N4O10

SMILES

– O([C@H]1[C@H](O[C@H]2O[C@]([C@@H](C)O)([C@@H](O)[C@H](O)[C@H]2N)[H])[C@@H](N)C[C@@H](N)[C@@H]1O)[C@@H]3O[C@]([C@@H](C)N)([C@@H](O)[C@H]3O)[H]

Pathway

– Others

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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