Edonerpic (maleate)

$85$780

Products Details

Product Description

– Edonerpic maleate is a novel neurotrophic agent which can inhibit amyloid-β peptides (Aβ).

Web ID

– HY-17631A

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– Neuroscience-Neurodegeneration

Molecular Formula

– C20H25NO6S

References

– [1]Hirata K, et al. A novel neurotrophic agent, T-817MA [1-{3-[2-(1-benzothiophen-5-yl) ethoxy] propyl}-3-azetidinol maleate], attenuates amyloid-beta-induced neurotoxicity and promotes neurite outgrowth in rat cultured central nervous system neurons. J Pharmacol Exp Ther. 2005 Jul;314(1):252-9.|[2]Kimura T, et al. T-817MA, a neurotrophic agent, ameliorates the deficits in adult neurogenesis and spatial memory in rats infused i.c.v. with amyloid-beta peptide. Br J Pharmacol. 2009 Jun;157(3):451-63.

CAS Number

– 519187-97-4

Molecular Weight

– 407.48

Compound Purity

– 98.68

SMILES

– OC1CN(CCCOCCC2=CC=C3C(C=CS3)=C2)C1.O=C(O)/C=CC(O)=O

Clinical Information

– Phase 2

Research Area

– Neurological Disease

Solubility

– DMSO : 100 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)

Target

– Amyloid-β

Pathway

– Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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